Investor Relations

Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 199 1,016.72 102.13 31,910,304
Mutual Fund 447 450.14 45.77 14,094,658
Insider 13 25.59 2.79 871,168

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 102 134.11 14.48 4,524,906
Sellers 104 -140.70 14.39 -4,496,712
Net -6.60 0.09 28,194

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 1,046.00 105.30 32,900,972
Top 10 Inst. 516.45 52.50 16,405,176
Top 20 Inst. 707.16 71.19 22,244,431
Top 50 Inst. 929.13 93.55 29,231,463

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 45 179.34 17.54 5,480,293
Aggressive Growth 2 0.98 0.10 30,431
Core Growth 34 144.23 14.05 4,388,720
Growth 9 34.13 3.40 1,061,142
Income 6 2.84 0.28 88,249
Income Value 2 2.64 0.26 82,157
Yield 4 0.20 0.02 6,092
Index 23 182.35 18.15 5,671,868
Other 78 508.50 51.86 16,203,697
Broker Dealer 17 19.14 1.91 595,364
GARP 26 169.42 16.88 5,274,238
Hedge Fund 30 308.14 31.75 9,920,923
Specialty 4 11.43 1.29 401,612
VC Private Equity 1 0.37 0.04 11,560
Value 28 105.75 10.52 3,288,240
Core Value 21 97.86 9.74 3,042,830
Deep Value 7 7.89 0.79 245,410

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
HealthCor Management, L.P. 2,571,910 8.23 81,800 3/31/19
Deerfield Management Company, L.P. 2,005,964 6.42 -72,411 3/31/19
BlackRock Institutional Trust Company, N.A. 1,983,366 6.35 -95,960 3/31/19
Invesco Advisers, Inc. 1,745,826 5.59 -2,627 3/31/19
Point72 Asset Management, L.P. 1,688,162 5.40 1,674,999 5/9/19
Wellington Management Company, LLP 1,618,147 5.18 -1,390,715 3/31/19
The Vanguard Group, Inc. 1,515,445 4.85 55,225 3/31/19
Millennium Management LLC 1,339,173 4.29 -8,185 3/31/19
AllianceBernstein L.P. 1,129,902 3.62 37,966 3/31/19
Federated Global Investment Management Corp. 807,281 2.58 -76,819 3/31/19
First Light Asset Management, LLC 720,240 2.31 18,842 3/31/19
State Street Global Advisors (US) 665,359 2.13 1,725 3/31/19
Westfield Capital Management Company, L.P. 652,781 2.09 -33,075 3/31/19
Fidelity Institutional Asset Management 632,426 2.02 600,310 3/31/19
Nuveen LLC 587,769 1.88 9,349 3/31/19
Ivy Investment Management Company 586,800 1.88 -258,180 3/31/19
APG Asset Management N.V. 561,536 1.80 404,780 6/30/18
William Blair Investment Management, LLC 528,404 1.69 138,780 3/31/19
Rock Springs Capital Management LP 465,000 1.49 -- 3/31/19
OppenheimerFunds, Inc. 438,940 1.40 8,938 3/31/19
Morgan Stanley Investment Management Inc. (US) 424,963 1.36 150,319 3/31/19
GLG Partners LP 399,800 1.28 68,313 3/31/19
Baron Capital Management, Inc. 396,288 1.27 638 3/31/19
Earnhardt (Lisa D) 386,665 1.24 -- 5/15/19
Geode Capital Management, L.L.C. 373,072 1.19 31,502 3/31/19
MIV Asset Management AG 373,000 1.19 -- 12/31/18
Northern Trust Investments, Inc. 370,218 1.18 4,004 3/31/19
Neuberger Berman, LLC 335,443 1.07 -26,780 3/31/19
Bellevue Asset Management AG 328,387 1.05 90,943 3/31/19
Broadfin Capital, L.L.C. 263,500 0.84 -24,400 3/31/19

* Insider values reflect direct beneficial ownership.

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